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Опубликована статья: Oxidative cross-coupling of secondary phosphine chalcogenides with amino alcohols and aminophenols: aspects of the reaction chemoselectivity // Kseniya O. Khrapova,  Anton A. Telezhkin,   Pavel A. Volkov,  Lyudmila I. Larina,   Dmitry V. Pavlov,   Nina K. Gusarova  and  Boris A. Trofimov  (https://doi.org/10.1039/D1OB00287B)

Abstract

Secondary phosphine chalcogenides react with primary amino alcohols under mild conditions (room temperature, molar ratio of the initial reagents 1 : 1) in a CCl4/Et3N oxidizing system to chemoselectively deliver amides of chalcogenophosphinic acids with free OH groups. Under similar conditions, mono-cross-coupling between secondary phosphine chalcogenides and 1,2- or 1,3-aminophenols proceeds only with the participation of phenolic hydroxyl to give aminophenylchalcogenophosphinic O-esters. The yields of the synthesized functional amides or esters are 60–85%.

Поздравляем авторский коллектив с завершением проекта по изучению окислительного сочетания фосфин халькогенидов с аминоспиртами и аминофенолами!

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